Naked mole rat hypothalamus chromatin state map

The naked mole-rat (NMR; Heterocephalus glaber) is a eusocial subterranean rodent with a highly unusual set of physiological traits, such as extreme longevity, that has attracted great interest amongst the scientific community. However, the genetic basis of most of these traits has not been elucidated. To facilitate our understanding of the molecular mechanisms underlying NMR physiology and behaviour, we generated a long-read chromosomal-level genome assembly of the NMR. To complement gene annotation and ascertain the organization of an NMR epigenome, we generated a chromatin state map of the female subordinate hypothalamus hypothalamus that included long-range promoter-enhancer interactions. This repository stores the ChIP-seq data used in the chromatin state map (H3K4me3, H3K4me2, H3K27Ac, H3K27me3, H3K36me3, H3K9me3, CTCF-whole-brain), and promoter and enhancer mapping of male subordinate hypothalamus samples (H3K4me3, H3K4me2).