Multivariable Models with different endpoints and adjusted for demographic factors alone (model 1), demographic factors and baseline CD4 count (model 2), and demographic factors and current CD4 count (model 3).

*Immuno-virological Discordance.
†per 100 cells/µl higher.
‡per log2 cells/µl higher.
§multivariable Poisson regression also adjusted for age, sex, transmission risk, race, region of cohort, calendar year of baseline, treatment naive/experienced, current or previous smoking, hepatitis B/C coinfection, whether or not on triple ART, number of treatment changes, diagnosis of anaemia, hypertension, impaired renal function, viral load at start of new regimen, time to viral suppression, previous AIDS or non-AIDS event.