Cytokine concentration in rectal lavages at acute time points post lubricant/control buffer application.

The p-values were calculated using unpaired t-tests (see Materials & Methods for details); the statistically significant ones are indicated in bold; CI = confidence interval.1We calculated the geometric means (GMs) of cytokines concentrations as shown, combining the measurements at 15m, 30m, 2- and 4-h acute time points. Levels of eight other cytokines were determined (see Methods) but many of the data points were below the assay limit of detection, and not suitable for accurate statistical analysesCytokine concentration in rectal lavages at acute time points post lubricant/control buffer application.