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The Impact of B-Cell Perturbations on Pneumococcal Conjugate Vaccine Response in HIV-Infected Adults

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Figshare2016-01-19 更新2026-04-29 收录
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https://figshare.com/articles/dataset/The_Impact_of_B_Cell_Perturbations_on_Pneumococcal_Conjugate_Vaccine_Response_in_HIV_Infected_Adults/122169
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Untreated HIV infection results in severe perturbations of the B-cell population and hyporesponsiveness to vaccination. We studied associations between circulating B-cell subsets and antibody response to pneumococcal conjugate vaccine in treated and untreated HIV patients. Ninety-five HIV-infected adults were grouped according to antiretroviral therapy (ART) and CD4+ cell count as follows: 20 ART-naïve (no prior ART), 62 ART-responders (received ART, and CD4 count >500 cells/µl), and 13 impaired responders (received ART for more than 3 years, and CD4 count
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2016-01-19
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