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Chromatin dynamics of p53 binding sites in IMR90

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NIAID Data Ecosystem2026-03-11 收录
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We report the chromatin modification dynamics at p53 binding sites upon treatment with DMSO or nutlin3-a (5uM) in IMR90 human lung fibroblasts using ChIP-seq and RNA-seq analyses. We assessed the genomewide changes in H3, H3K4me3, H3K4me2, H3K4me1, H3K27ac, H4K16ac, RNA polymerase II, and p53 in response to p53 activation. ChIP-seq of 8 histone modifications or proteins for 2 conditions in 1 cell line.

创建时间:
2019-05-15
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