Composition for cleaving a target DNA comprising a guide RNA specific for the target DNA and Cas protein-encoding nucleic acid or Cas protein， and use thereof

The present invention relates to targeted genome editing in eukaryotic cells or organisms. More specifically， the present invention relates to compositions for cleaving target DNA in eukaryotic cells or organisms， and uses thereof， comprising a nucleic acid or Cas protein encoding a Cas protein and a guide RNA specific for the target DNA. The present invention relates to targeted genome editing in eukaryotic cells or organisms. More particularly， the present invention relates to a composition for cleaving a target DNA in eukaryotic cells or organisms comprising a guide RNA specific for the target DNA and Cas protein-encoding nucleic acid or Cas protein， and use thereof. The present invention relates to targeted genome editing in eukaryotic cells or organisms. More particularly， the present invention relates to a composition for cleaving a target DNA in eukaryotic cells or organisms comprising a guide RNA specific for the target DNA and Cas protein-encoding nucleic acid or Cas protein， and use thereof.