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Non-canonical AMPA receptor blockade reduces lymph node egress and neuroinflammation [scRNA-seq]

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE249327
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资源简介:
Disturbances in the glutamatergic system have been linked to neuronal pathology. Investigating therapeutic translation, we discovered immune-related effects for the selective non-competitive AMPA receptor blocker perampanel in mouse models of multiple sclerosis. Comparative gene expression profiling analysis of RNA-seq data for EAE perampanel treated mice and controls
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2025-09-12
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