Nonsense-mediated mRNA decay (NMD) is a translation-dependent mRNA surveillance pathway that eliminates transcripts with premature termination codons. Several studies have tried defined the features g

NIAID Data Ecosystem40

RNAseq in Smg7-/- and parental immortalized mouse fibroblasts

无义介导mRNA降解

TNFα诱导凋亡的转录调控

Nonsense mediated decay (NMD) proteins are responsible for the surveillance and degradation of aberrant RNAs. Among these, SMG7 is a novel regulator of TNFa induced apoptosis; however, its effect on t

NIAID Data Ecosystem20

Nonsense-Mediated Decay restricts lncRNAs levels in yeast unless blocked by double-stranded RNA structure

无义介导mRNA降解

非编码RNA调控

Antisense long non-coding (aslnc)RNAs represent a substantial part of eukaryotic transcriptomes that are, in yeast, controlled by the Xrn1 exonuclease

Alliance of Genome Resources40

Genome-wide analysis of Human Upf1, SMG5, SMG7 and PNRC2 downregulated substrates in HeLa cell

无义介导mRNA降解

siRNA沉默转录组分析

Analysis of cellular NMD (Nonsense-mediated mRNA decay) substrates that regulated by Upf1, SMG5, SMG7 and/or PNRC2 in HeLa cell. The hypothesis tested in the present study was that endogenous NMD subs

NIAID Data Ecosystem30

Chlamydomonas reinhardtii splicing factors and SMG1. Chlamydomonas reinhardtii strain:137c

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