dSysMap

dSysMap (Mapping of Human disease-related mutations at the systemic level) displays Human disease-related mutations on the structural interactome. Mapping of mutations on protein structures and on interaction interfaces allows you to visualize the region of the interactome that they affect and helps in rationalizing their mechanism of action.dSysMap（全系统人类疾病相关突变图谱，Mapping of Human disease-related mutations at the systemic level）可在结构互作组（structural interactome）上可视化呈现人类疾病相关突变。针对蛋白质结构与互作界面上的突变开展映射分析，能够直观展示其影响的互作组区域，同时有助于阐明其作用机制。

搜集汇总

背景与挑战

背景概述

dSysMap是一个在系统水平上映射人类疾病相关突变的数据集，它将突变定位到结构相互作用组中。通过在蛋白质结构和相互作用界面上进行映射，该数据集能够可视化突变影响的相互作用区域，从而有助于理解其作用机制。