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Exome sequencing of ENU mutagenised mice

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NIAID Data Ecosystem2026-05-26 收录
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We conducted a sensitised ENU mutagenesis screen to identify thrombosis modifier genes. After mutagenesis, we screened for mice carrying the otherwise lethal genotype FVL/FVL TFPI+/-. These mice were subjected to whole exome sequencing in order to map the induced mutations and the underlying genes responsible for the survival phenotype.

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2018-08-04
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