five

Phase_variable_epigenetic_control_in_firmicutes

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/ERP019792
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In 2014 we have published independently that the human pathogen Streptococcus pneumoniae has in its core-genome a phase variable type I restriction modification system which influences via epigenetic control gene expression and virulence (Manso et al., Nat Commun. 2014, 5:5055; Croucher et al., Nat Commun. 2014. 5:5471). The main aim of the project is to translate this biological novelty and unicum into a general paradigm.
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2021-02-04
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