five

Chemical chaperone screening for Pelizaeus-Merzbacher disease

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE124034
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We investigated the changes in the overall gene expression in MO3.13 cells induced by PLP1A243V and piracetam using RNA microarray analyses. We compared gene expression between PLP1WT and PLP1A243V and the expression profile in MO3.13 stably expressing PLP1A243V with/without piracetam. We extracted 3 kinds of RNA using the RNeasy® Mini kit (QIAGEN N.V., Venlo, Netherlands) in MO3.13 cells stably expressing PLP1A243V 24 h after adding piracetam at 10 µM, PLP1A243V without piracetam, and PLP1WT.
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2019-07-10
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