ChIP-seq of H1299 cells stably transfected with empty vector or the p53 mutant R273H. ChIP-seq of H1299 cells stably transfected with empty vector or the p53 mutant R273H

This experiment was performed to determine which gene promoters mutant p53 binds and transcriptionally regulates in order to understand how mutant p53 accomplishes its gain of function phenotype.