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Expansion of UBTR012574 Chemical Series

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NIAID Data Ecosystem2026-05-02 收录
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Expansion of the chemical series of UBTR012574 (KD= 10 ± 0.1 µM) by docking analogue compounds from the Enamine REAL database and SciFinder against the USP5 zinc finger ubiquitin-binding domain (ZnF-UBD) to prioritize compound ordering. The binding potency of the ordered compounds against USP5 ZnF-UBD was assessed with a surface plasmon resonance (SPR) assay.

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2024-07-22
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