Genome-wide analysis of m6A-linked DRACH signatures across 272 human-derived MERS-CoV genomes

This dataset provides the first comprehensive catalog of m6A-associated DRACH motifs (D = A/G/T, R = A/G, H = A/C/T) across 272 human-derived Middle East respiratory syndrome coronavirus (MERS-CoV) genomes, sourced from NCBI and analyzed using a reproducible bioinformatics pipeline. Despite limitations in inter-genome alignment fidelity (leading to inflated SNP counts), DRACH motif identification remains robust as it relies solely on local sequence context. The analysis reveals an average of 533.7 DRACH motifs per genome, consistent with the dense regulatory landscape of coronavirus RNA. This resource enables future studies on MERS-CoV epitranscriptomics, host-virus RNA modification interplay, and the role of m6A in viral replication and immune evasion. All of the raw data / processed data are included for full reproducibility. This dataset is part of larger study alpha/merbeco/sarbeco genuses. Data processed by: [e-mail]