Data and code for: Physiological architecture and evolutionary origins of cellular adaptability

Processed data and analysis code accompanying: Dea A, Lan Y, Doran BA, Ali A, Igarashi MG, Dyer L, Aksianiuk V, Pincus D, Raman AS. Physiological architecture and evolutionary origins of cellular adaptability. Science (2026). Contents include bulk and single-cell RNA-seq processed matrices, UMAP coordinates, mutual information CDFs (SCALES analysis), polysome trace data, single-cell imaging quantification, competitive fitness assays, derived-strain variant calls, and Python image analysis pipelines. Raw single-cell and bulk RNA-seq data are deposited in GEO (accession pending). Whole-genome sequencing data are deposited in SRA/NCBI (accession pending). Raw microscopy images (~20 GB) are available upon request from the corresponding authors.