MPM cell lines

RNA-sequencing data for 12 MPM cell lines treated with 0.1% DMSO or 1 µM palbociclib for 9-10 days.Experiment was performed in duplicates for sensitive cells (MPM08, MPM21, MPM38, MPM57, MPM59, Meso11, Meso13, Meso34 and Meso56) and only once for resistant cells (MPM31, MPM34 and MPM36) except for Meso11 which was done in triplicates. For Meso11, Meso13, Meso34 and Meso56, a drug washout of 48 hours was also performed. 4 MPM cell lines (MPM31, MPM34, MPM59 and MPM66)were also analyzed in untreated condition. 2 FASTQ files for each sample (n=56) (paired)

本研究收集了12种不同来源的乳腺癌细胞系（MPM细胞系）的RNA测序数据，这些细胞系在0.1%的二甲基亚砜（DMSO）或1微摩尔_palbociclib_的药物处理下培养9至10天。针对对药物敏感的细胞系（包括MPM08、MPM21、MPM38、MPM57、MPM59、Meso11、Meso13、Meso34和Meso56），实验进行了重复操作；而对于耐药细胞系（MPM31、MPM34和MPM36），实验仅进行了一次，但Meso11细胞系则进行了三重重复。对于Meso11、Meso13、Meso34和Meso56细胞系，还额外进行了48小时的药物清除处理。此外，对4种细胞系（MPM31、MPM34、MPM59和MPM66）在未处理条件下也进行了分析。每个样本（共计56个）均生成了2个FASTQ文件。