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Crystal structure of STK17b (DRAK2) in complex with UNC-AP-194 probe

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Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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Crystal structure of STK17b (DRAK2) in complex with UNC-AP-194 probe Descriptor: 1,2-ETHANEDIOL, 2-[6-(1-benzothiophen-2-yl)thieno[3,2-d]pyrimidin-4-yl]sulfanylethanoic acid, Serine/threonine-protein kinase 17B Authors: Chaikuad, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Drewry, D, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2020-02-26 Release date: 2020-03-11 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.95 Å) Cite: A Chemical Probe for Dark Kinase STK17B Derives Its Potency and High Selectivity through a Unique P-Loop Conformation. J.Med.Chem., 63, 2020

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2020-02-26
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