Combining genotypes and T cell receptor distributions to infer genetic loci determining V(D)J recombination probabilities: validation cohort meta data and parsed TCR repertoire data

Meta data corresponding the the validation cohort for the paper, "Combining genotypes and T cell receptor distributions to infer genetic loci determining V(D)J recombination probabilities" by Magdalena L Russell, Aisha Souquette, David M Levine, Stefan A Schattgen, E Kaitlynn Allen, Guillermina Kuan, Noah Simon, Angel Balmaseda, Aubree Gordon, Paul G Thomas, Frederick A Matsen IV, and Philip Bradley. These meta data include: 

(1) SNP genotypes for the two SNPs which overlap with the discovery cohort
         - (nicaragua_snp_genotypes_ints.tsv) -- SNP genotypes as integers
         - (nicaragua_snp_genotypes_strings.tsv) -- SNP genotypes as allele strings 
(2) the ancestry PCs for each individual in the validation cohort (nicaragua_snp_ancestry_PCA.tsv)
(3) a file including IMGT genes and sequences used for parsing TCRB repertoire data (human_vj_allele_cdr3_nucseqs.tsv)
(4) a file including IMGT genes used for parsing TCRA repertoire data (human_vj_alleles_alpha.tsv)
(5) Parsed TCRA repertoire data (nicaragua_parsed_TCRA.tgz)
(6) Parsed TCRB repertoire data (nicaragua_parsed_TCRB.tgz) 

Corresponding raw validation cohort TCR repertoire data is available here: https://www. ncbi.nlm.nih.gov/bioproject/PRJNA762269 (The BioProject database, accession number: PRJNA762269)

Software tools designed to work with these data are available here: https://github.com/phbradley/tcr-gwas