Baseline characteristics of participants in the baseline only and longitudinal analysis cohorts.

†Baseline only = participants with only 1 DEXA performed; includes 14 screen failures.‡TDF/placebo = participants randomized to TDF or placebo who had at least 1 follow-up DEXA and were included in the longitudinal cohort.*P value compares TDF vs. placebo arms of longitudinal cohort.¥For baseline only group, alcohol and recreational drug use data available for 12/26 participants who enrolled in the study. DEXA, dual energy X-ray absorptiometry; TDF, tenofovir disoproxil fumarate; BMD, bone mineral density.