Gene expression analysis of gain-of-function mutant p53 knock-in cells
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https://www.ncbi.nlm.nih.gov/sra/DRP011656
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资源简介:
We generated p53 R175H or R248Q missense mutation knock-in cells, known as gain-of-function (GOF) mutations. To confirm the cell behaviors of GOF p53, we performed an RNA sequencing (RNA-seq) analysis to compare the differences in genome-wide gene expression among p53-wild-type, -KO, -R175H or -R248Q cells.
创建时间:
2024-06-11



