Several mouse lines have been developed to target microglia genetically; however, they lack specificity. Here, we use ribosome tagging and immunoprecipitation coupled to RNA-Seq in our newly developed
This study examines the role of early exposure to gut microbes and poor diet on microglial function in mice. Groups = control (CON), malnourished (MAL), and malnourished + microbial exposure (E/MALBG)
High grade glioma in mice and human have been shown to be greatly impacted by the infiltration of macrophages in the tumor, but it is unknown whether the populations of macrophages in the tumors may h