Central cornea thickness Genome Wide Association Meta Analyses - Summary statistics
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https://datashare.ed.ac.uk/handle/10283/2976
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资源简介：
Results from the meta-analyses of genome-wide association studies for central cornea thickness in human. Corneal thinning is a common feature of rare Mendelian connective tissue disorders, such as Ehlers-Danlos syndrome (EDS), Marfan syndrome and osteogenesis imperfecta (OI), and extreme thinning is a clinical characteristic of brittle cornea syndrome . Thinner CCT is also observed in more common ocular disorders such as keratoconus, the leading cause of corneal transplants worldwide. Dataset pertaining to the publication “Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases” which uses genetic variants imputed to the 1000 Genomes phase 1 reference in cohorts of European ancestry (14 cohorts,N=17,803) and Asian ancestry (5 cohorts, N=8,107) .
提供机构：
University of Edinburgh. Medical Research Council Human Genetics Unit. Institute of Genetics and Molecular Medicine. (please see attached file for full list of data publishers)
创建时间：
2017-12-20
