Flanking bacterial genes can predict sr2WO-like regions in B-Wolbachia.

Sr2WO recombinase sequences are adjacent to core bacterial genes in the Wolbachia chromosome (defined as the 5’-end of the prophage region). The adjacent bacterial genes in the wPip genome, a B-Wolbachia that lacks sr2WO prophages, correlate with 3’- boundaries of the predicted prophage or WO-like Island region. prsA refers to ribose-phosphate diphosphokinase; tkt refers to transkelotase; tpiA refers to triose-phosphate isomerase; murD refers to UDP-N-acetylmuramoylalanine: D-glutamate ligase. (XLSX)