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DNA methylation profiling of human prefrontal cortex neurons in heroin users shows significant difference between genomic contexts of hyper- and hypomethylation and a younger epigenetic age

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE98203
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Illumina 450K Infinium microarray profiling of DNA methylation in FACS-separated neuronal nuclei from the postmortem orbitofrontal (OF) cortex of heroin users, controls and sucide individuals. Genomic DNA was isolated from FACS-sorted human brain neuronal nuclei. DNA was bisulfite-converted and hybridized to the Illumina Infinium 450K Human Methylation Beadchip array. 88 subjects were analyzed.
创建时间:
2021-07-25
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