Homo sapiens Transcriptome or Gene expression

Malignant mesothelioma (MM) is an asbestos related tumour affecting cells of serosal cavities. More than 70% of MM patients develop pleural effusions which often contain tumour cells, representing a readily accessible source of tumour cells for genetic analysis. Although common somatic mutations and losses have been identified in solid MM tumours, the characterization of tumour cells within pleural effusions is limited.