The essential role of heparan sulfate in the entry of PDCoV and other porcine coronaviruses

Figure 1. Heparin sodium treatment of cells inhibits PDCoV infection.
Figure 2. Heparin sodium treatment inhibits infection by multiple coronaviruses.
Figure 3. Mitoxantrone, an HS-binding drug, inhibits PDCoV infection.
Figure 4. The effects of genetic ablation of HS biosynthesis genes on PDCoV infection.
Figure 5. SLC35B2, EXT1 and NDST1 HS biosynthesis genes are required for efficient infection by PEDV, SADS-CoV and TGEV.
Figure 6. SLC35B2, EXT1 and NDST1 gene KO in LLC-PK1 cells reduces PDCoV attachment.
Figure 7. Impact of the overexpression of HS biosynthesis genes on porcine coronavirus infection.