Regulatory CD4+ T cells (Tregs) are functionally distinct from conventional CD4+ T cells (Tconvs). To understand Treg identity, we compared by proteomics and transcriptomics human naïve (n) and effect

NIAID Data Ecosystem60

A Miniaturized Chemical Proteomic Approach for Target Profiling of Clinical Kinase Inhibitors in Tumor Biopsies

共价抑制剂靶点分析

活细胞蛋白质组学

While targeted therapy based on the idea of attenuating the activity of a preselected, therapeutically relevant protein has become one of the major trends in modern cancer therapy, no truly specific t

NIAID Data Ecosystem40

SIGLEC-G-APEX2 proximity labeling and proteomic profiling in primary mouse MDMs

蛋白质邻近标记

活细胞蛋白质组学

SIGLEC-G-APEX2 proximity labeling and proteomic profiling in primary mouse MDMs

integrated proteome resources80

Social Network Architecture of Human Immune Cells Unveiled by Quantitative Proteomics

活细胞蛋白质组学

细胞器间通讯

The immune system is unique in its dynamic interplay between numerous cell types. However, a system-wide view of how immune cells communicate to protect against disease has not been established. Here,

NIAID Data Ecosystem40

Changed acetylation of THP-1 and U937 proteins were detected by SILAC.

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