Ablation analysis of FSA on simulated unrelated protein and DNA sequences.

Ablation analysis of FSA on the unrelated sequence benchmarks of Table 4 : Comparisons of the accuracies (Acc), sensitivities (Sn) and positive predictive values (PPV) of FSA with different components enabled or disabled. From top to bottom, FSA was run in default mode, –fast mode, with learning disabled, with iterative refinement disabled, and with 1 set (rather than 2 sets) of indel states; these options were then repeated for maximum-sensitivity mode (–maxsn). Query-specific learning helps to make FSA robust to non-homologous sequence.