Molecular distinctions between proprioceptors supplying Tibialis anterior (TA) and Gastrocnemius (GS) muscles [array]

Muscle-specific populations of proprioceptive sensory neurons form selective connections with spinal motor neurons, implying the existence of molecular distinctions between proprioceptor subpopulations. Here, we compare the gene expression profiles of proprioceptors that supply an antagonistic muscle pair functioning at a single hindlimb joint. TA and GS muscles in a Pv::YFP reporter line were injected at p0 with ctb-555; retrogradely labeled proprioceptors were manually isolated at p1 and pooled to form 25-30 neuron samples. *** Processed data (i.e., Partek-generated log2 GCRMA signals) are unavailable. ***