Structure of Human ROS1 Kinase Domain in Complex with Crizotinib
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Structure of Human ROS1 Kinase Domain in Complex with Crizotinib Descriptor: 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS Authors: McTigue, M, Deng, Y, Liu, W, Brooun, A, Stewart, A. Deposit date: 2012-11-08 Release date: 2013-06-12 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Acquired Resistance to Crizotinib from a Mutation in Cd74-Ros1 N.Engl.J.Med., 368, 2013
创建时间:
2012-11-08



