Enantioselective Synthesis of (Thiolan-2-yl)diphenylmethanol and Its Application in Asymmetric, Catalytic Sulfur Ylide-Mediated Epoxidation
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https://figshare.com/articles/dataset/Enantioselective_Synthesis_of_Thiolan_2_yl_diphenylmethanol_and_Its_Application_in_Asymmetric_Catalytic_Sulfur_Ylide_Mediated_Epoxidation/2407843
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资源简介:
This
work describes an expeditious and efficient preparation of enantiopure
(thiolan-2-yl)diphenylmethanol (2) featuring a double
nucleophilic substitution and Shi epoxidation as key steps. One of
the applications of its benzyl ether derivative to asymmetric sulfur
ylide-mediated epoxidation with up to 92% ee (14 examples) was also
demonstrated herein.
创建时间:
2013-06-07



