Dnmt3a deficiency in the skin

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https://www.ncbi.nlm.nih.gov/sra/SRP291379

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Whole genome bisulfite sequencing of epidermal cells of Dnmt3a-deficient mice

创建时间：

2020-11-06

Dnmt3a deficiency in the skin

Whole genome bisulfite sequencing of epidermal cells of Dnmt3a-deficient mice

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DNA methylation of dnmt3a deficient Kras lung tumors and dnmt3a wt Kras lung tumors

To examine whether Dnmt3a deficiency resulted in genomic methylation changes we performed an unbiased methylome analysis. Methylated DNA isolated from three Dnmt3a deficient and two WT tumors was immu

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The role of DNMT3A in AITL. The role of DNMT3A in AITL

To investigate the role of DNMT3A in AITL, single cell RNA-seq (scRNA-seq) is performed to analysis the lymph nodes generated from the control, RHOAG17V and RHOAG17V DNMT3AR882H AITL mice. The mitoQC

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Investigation of mutational signatures associated with DNMT3A deficiency

Mutational signatures have been shown to be attributable to specific genetic contexts, such as mutations in DNA repair genes. DNMT3A is a DNA methyltransferase that helps maintain the DNA methylation

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Gene expression changes in mouse forebrain deficient in Dnmt1 and Dnmt3a

Two major DNA methylation-catalyzing enzymes, Dnmt1 and Dnmt3a, are expressed in postmitotic neurons, but their function in the adult central nervous system is unclear. We generated conditional mutan

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