Mesenchymal EZH2 maintains uterine adenogenic homeostasis

To determine the mesenchymal function of EZH2 in the mouse uterus, we generated Ezh2 cKO mice using anti-Mullerian hormone type 2 (Amhr2)-Cre that is expressed in the mesenchymal and not epithelial compartment of the uterus Overall design: We performed RNA-sequencing in the uteri of Ezh2 cKO mice and controls at the age of postnatal day 10: Ctrl, PD10, 1 = HISAT2.on.data.18.and.data.17 Ctrl, PD10, 2 = HISAT2.on.data.22.and.data.21 Ctrl, PD10, 3 = HISAT2.on.data.26.and.data.25 Ctrl, PD10, 4 = HISAT2.on.data.30.and.data.29 cKO, PD10, 1 = HISAT2.on.data.34.and.data.33 cKO, PD10, 2 = HISAT2.on.data.38.and.data.37 cKO, PD10, 3 = HISAT2.on.data.42.and.data.41 cKO, PD10, 4 = HISAT2.on.data.46.and.data.45