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LINE1 and PRC2 control nucleolar organization and repression of the 8C-state in human ESCs. LINE1 and PRC2 control nucleolar organization and repression of the 8C-state in human ESCs

NIAID Data Ecosystem2026-05-01 收录

细胞表观遗传调控

核仁组织

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA974446 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2023-05-19

细胞表观遗传调控

iNKT细胞发育

Invariant natural killer T (iNKT) cells are a specific innate-like counterpart of T lymphocytes, which response to lipid-based antigens and provide a functional bridge between the innate and adaptive

NIAID Data Ecosystem40

Immune-restricted epigenetic reader SP140 maintains macrophage identity and activation states critical to intestinal homeostasis [ChIP-seq]. Homo sapiens

细胞表观遗传调控

克罗恩病免疫机制

Introduction: SP140 is a bromodomain/plant homeo domain (PHD)-containing reader with immune-restricted expression, and single nucleotide polymorphisms (SNPs) within SP140 associate with Crohn’s diseas

NIAID Data Ecosystem20

NSD1-deposited H3K36me2 directs de novo methylation in the mouse male germline and counteracts Polycomb-associated silencing

细胞表观遗传调控

DNA从头甲基化机制

While de novo DNA methylation (DNAme) in mammalian germ cells is dependent upon DNMT3A and DNMT3L, oocytes and spermatozoa show distinct patterns of DNAme. In mouse oocytes, de novo DNAme requires the

Alliance of Genome Resources00

Genome-wide binding profiles of PU.1 in unstimulated and Candida albicans stimulated HoxER-PU.1 WT neutrophils. Genome-wide binding profiles of PU.1 in unstimulated and Candida albicans stimulated HoxER-PU.1 WT neutrophils

细胞表观遗传调控

宿主-病原体相互作用

Neutrophils are essential first line defense cells against invading pathogens, yet their inappropriate activation contributes to immunological diseases and can cause collateral tissue damage. However,

NIAID Data Ecosystem20

Role of Fft3 in nuclear organization [MNase-seq]. Schizosaccharomyces pombe

染色质结构

核仁组织

In eukaryotic cells, local chromatin structure and chromatin organization in the nucleus both influence transcriptional regulation. At the local level, the Fun30 chromatin remodeler Fft3 is essential

NIAID Data Ecosystem20

LINE1 and PRC2 control nucleolar organization and repression of the 8C-state in human ESCs. LINE1 and PRC2 control nucleolar organization and repression of the 8C-state in human ESCs

资源简介：

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