BCCM/GeneCorner - Plasmid Collection

The BCCM/GeneCorner Plasmid Collection warrants the long-term storage and distribution of plasmids, microbial host strains and DNA libraries of fundamental, biotechnological, educational or general scientific importance.
The focus is on the collection of recombinant plasmids that can replicate in a microbial host strain, with main interest for:
empty cloning plasmids useful for recombinant (over)expression of proteins of interest in bacteria, yeast, fungi, insect cells, plant and animal cells; (expression) plasmids carrying specific protein-coding genes and derivatives from a wide range of organisms (human, mouse, various bacterial species, ...); expression plasmids with specific non-coding genes such as shRNA and miRNA; plasmids for mouse genetic engineering, allowing the generation of transgenic mice. BCCM/GeneCorner also accepts natural and genetically modified animal or human cell lines, including hybridomas, as well as other genetic material, in the safe deposit and patent deposit collections.

BCCM/GeneCorner质粒库（BCCM/GeneCorner Plasmid Collection）可对具有基础研究、生物技术应用、教育或通用科学研究价值的质粒、微生物宿主菌株以及DNA文库提供长期保藏与分发服务。
该库的收藏重点为可在微生物宿主菌株中复制的重组质粒，主要关注以下几类载体：可用于在细菌、酵母、真菌、昆虫细胞及动植物细胞中重组（过量）表达目标蛋白的空白克隆质粒；携带来自人类、小鼠、多种细菌物种等各类生物体的特定蛋白编码基因及其衍生序列的（表达）质粒；搭载shRNA、miRNA等特定非编码基因的表达质粒；可用于小鼠基因工程、助力转基因小鼠构建的质粒。此外，BCCM/GeneCorner还接收天然及转基因动物或人类细胞系（包括杂交瘤细胞）与其他遗传材料，将其纳入安全保藏库及专利保藏库馆藏范畴。