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Transcriptome profiling of taxane-resistant, castration-resistant prostate cancer cells versus parental control cells

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下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP309593
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The purpose of the study was to assess the transcriptomic differences between taxane-resistant cell lines and parental control cells to identify drivers of resistance. Overall design: A total of 6 samples were analyzed in this study, C4-2B and DU145 (parental cells), docetaxel-resistant C4-2B and DU145 cell lines TaxR and DTXR, and cabazitaxel-resistant, docetaxel-resistant derivative cell lines, CabR and CTXR. Cell were harvested, RNA was Trizol extracted, and samples submitted for RNA-sequencing.
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2021-08-24
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