The FK1 domain of FKBP51 in complex with the macrocyclic SAFit analog 12c/p
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The FK1 domain of FKBP51 in complex with the macrocyclic SAFit analog 12c/p Descriptor: 3-cyclohexyl-19,20-dimethoxy-19-methyl-11,20-dioxa-5-aza-1lambda5-polona-1,19lambda5-dithia-18-azanida-1lambda5-stannapentacyclo[19.2.1.05,10.013,18.018,22]tetracosane-4,12-quinone, Peptidyl-prolyl cis-trans isomerase FKBP5 Authors: Meyners, C, Buffa, V, Walz, C, Hausch, F. Deposit date: 2024-09-09 Release date: 2025-01-15 Last modified: 2025-03-19 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Conformational Plasticity and Binding Affinity Enhancement Controlled by Linker Derivatization in Macrocycles. Angew.Chem.Int.Ed.Engl., 64, 2025
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2024-09-09
