The present study aimed to investigate the protective effects of salidroside on chronic heart failure (CHF) in rats and to explore the underlying mechanisms. One hundred SD rats were randomly divided
In this study, we employed descending aortic constriction (DAC) technique to establish a minipig heart failure model. The cardiac phenotypes, pathological and cellular changes, fibrotic signaling acti
We show that the RNA binding protein Human antigen R is activated in the failing human heart and its inhibition, by genetic deletion or pharmacological inhibition, prevents the progression to heart fa
Neurons exert a pivotal role in the preservation of cardiac physiological function. However, there is a lack of explanation about the mechanism of cardiac neurons in the pathogenesis of cardiac dysfun