Whole transcriptome Identification of direct targets of miR-199a-5p and miR-424-3p using biotinylated pull-downs found that both miRNAs are likely to have a role in the cell cycle. HEK293T cells were

NIAID Data Ecosystem60

Transcriptomic profiling of untreated and oxidative stress treated Wild-type and IPO13-/- mouse embryonic stem cells to study the role of IPO13 in transcriptional response to stress.

应激响应转录组

干细胞功能基因组学

Purpose: The importin (IPO) superfamily member IPO13 is able to mediate nuclear transport bidirectionally. To better understand IPO13 involvement in cellular signalling, we performed transcriptomic an

NIAID Data Ecosystem40

RNA sequencing LSK cells after Cxxc5 knockdown

干细胞功能基因组学

基因敲低转录组分析

To study the effect of knockdown of Cxxc5 on stem/progenitor cells, we used retrovirus to knockdown Cxxc5 expression in the LSK cells. We used this as a surrogate to study the function of Cxxc5 in mou

NIAID Data Ecosystem70

Identification of Novel miR-21 Target Proteins in Multiple Myeloma Cells by Quantitative Proteomics

肿瘤蛋白质组学

microRNA靶标

Substantial evidence indicates that microRNA-21 (miR-21) is a key oncomiR in carcinogenesis and is significantly elevated in multiple myeloma (MM). In this study, we explored the role of miR-21 in hum

NIAID Data Ecosystem40

Biochemical Identification of Targets of Individual MicroRNAs in Mouse Embryonic Stem Cells

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