Identification of the genes under the control of the transcription factor Prdm12 in somatosensory neurons

Prdm12, a novel key regulator of the Nerve Growth Factor-TrkA signaling pathway, is required for nociceptive sensory neuron development RNA-seq analysis in triplicate of the transcriptome of thoracic dorsal root ganglia with associated spinal cord of E11.5 Prdm12 KO and WT embryos.Prdm12是神经生长因子-酪氨酸激酶受体A（Nerve Growth Factor-TrkA）信号通路的新型关键调控因子，其对于伤害感受性感觉神经元的发育不可或缺。本数据集包含对E11.5天Prdm12基因敲除（KO）与野生型（WT）小鼠胚胎的胸段背根神经节及其相连脊髓的转录组进行的三次重复RNA测序（RNA-seq）分析。