BackgroundAddition of oxaliplatin to adjuvant 5-FU has significantly improved the disease-free survival and served as the first line adjuvant chemotherapy in advanced colorectal cancer (CRC) patients.
Vascular inflammation and myofibroblast activation by TGF-Ã1 are key, yet-to-be-fully-understood pathological processes in fibrosis. Here we report the development of a novel human Tendon-on-a-Chip (
The responses of individual organoid to different treatments (irradiation, 5-Fu and CPT-11): data for Patient-derived organoids predict chemoradiation responses of locally advanced rectal cancer.
Organoid cultures derived from colorectal cancer (CRC) samples are increasingly used as preclinical models for studying tumor biology and the effects of targeted therapies under conditions capturing i
