Expression of immune-inducible genes in Drosophila melanogaster whole fly samples upon Micrococcus luteus infection for 24h

Transcriptome profiling of immune-responsive genes in Drosophila melanogaster during Gram-positive bacterial infection was performed. The most highly induced gene by Micrococcus luteus infection was a novel gene CG44404, named Induced by Infection (IBIN). In the Flybase release FB2019_4 (22.8.2019) IBIN is annotated as coding for a short peptide. In the transcriptome analysis, fourteen immune-inducible long non-coding RNA (lncRNA) genes (Fold Change > 3) were also found. Overall design: Three biological replicates (A,B&C) containing 5 flies each are analyzed per condition (non-infected vs. M.luteus infected for 24h)