Super-enhancer H3K27ac CUT& Tag sequencing of six human gastric cancer tissue samples

CUT& Tag was performed using H3K27ac antibody to identify the super-enhancers of GC with different growth patterns through ROSE algorithm. Comparison of SE-driven oncogenes in infiltrative and expanding GC was carried out to screen key signatures and candidate genes. Six GC samples were collected, and H3K27ac CUT&Tag sequencing was performed for the first time to identify of GC SEs