Increased DNA Methylation of Dnmt3b-Targets Impairs Leukemogenesis (RRBS)

ChEBI2016-01-11 更新2026-07-12 收录

白血病表观遗传学

甲基化功能研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-71039 数据链接链接失效反馈

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Increased DNA Methylation of Dnmt3b-Targets Impairs Leukemogenesis (RRBS)

创建时间：

2016-01-11

BET inhibition releases the Mediator complex from specific cis elements in acute myeloid leukemia cells (ChIP-Seq II)

白血病表观遗传学

染色质免疫沉淀测序

Genome occupancy profiling by high throughput sequencing ChIP-seq of Brd4 with or without Doxycycline treatment to induce Med12 or Med23 shRNAs in MLL-AF9 transformed acute myeloid leukemia cells (RN2

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High-resolution Nanopore methylome-maps reveal random hyper-methylation at CpG-poor regions as driver of chemoresistance in leukemias.

白血病表观遗传学

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Aberrant DNA methylation at CpG dinucleotides is a hallmark of cancer and is associated with the emergence of resistance to anti cancer treatment, though molecular mechanisms and biological significan

NIAID Data Ecosystem50

Homo sapiens Epigenomics. Homo sapiens

白血病表观遗传学

甲基化DNA生物标志物

DNA methylation study of pediatric t(8;21) AML patients who underwent or not relapse

NIAID Data Ecosystem20

Methylation and gene expression data obtained from Dnmt3b+/+, Dnmt3bD/D and Dnmt3bCI/CI MYC induced T-cell lymphomas (MTCLs).. Methylation and gene expression data obtained from Dnmt3b+/+, Dnmt3bD/D and Dnmt3bCI/CI MYC induced T-cell lymphomas (MTCLs).

淋巴瘤表观遗传学

甲基化功能研究

DNA methylation has suppressive effects on gene transcription and it is involved in a variety of physiologic processes, including development and cancer. As we and others demonstrated, Dnmt3b is a tum

NIAID Data Ecosystem50

Methylation profiling of leukemia cell lines

白血病表观遗传学

CpG甲基化

Methylation of CpG islands is associated with transcriptional repression and, in cancer, leads to the abnormal silencing of tumor-suppressor genes. We developed a novel and robust technique that allow

NIAID Data Ecosystem30

Increased DNA Methylation of Dnmt3b-Targets Impairs Leukemogenesis (RRBS)

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