Diastereo- and Enantioselective Construction of Oxindole-Fused Spirotetrahydrofuran Scaffolds through Palladium-Catalyzed Asymmetric [3+2] Cycloaddition of Vinyl Cyclopropanes and Isatins
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https://figshare.com/articles/dataset/Diastereo_and_Enantioselective_Construction_of_Oxindole_Fused_Spirotetrahydrofuran_Scaffolds_through_Palladium_Catalyzed_Asymmetric_3_2_Cycloaddition_of_Vinyl_Cyclopropanes_and_Isatins/2402821
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资源简介:
A novel
asymmetric formal [3+2] cycloaddition of vinyl cyclopropanes and isatins
in the presence of Pd2(dba)3 and the chiral
imidazoline-phosphine ligand (aS,R,R)-L3 has been developed, affording the corresponding highly functionalized
oxindole-fused spirotetrahydrofuran frameworks in good yields along
with good diastereo- and high enantioselectivities under mild conditions.
创建时间:
2016-02-19



