Whole-genome sequencing of multidrug-resistant Staphylococcus aureus from companion animals in Japan

S. aureus strains derived from companion animals in Japan have a strong tendency toward multidrug resistance. Although companion animal-derived strains are considered to be genetically similar to human-derived strains, it is possible that S. aureus has undergone genome evolution by being carried by companion animals. Therefore, this study aims to elucidate the genome evolution and drug resistance mechanism of S. aureus by conducting whole genome analysis to elucidate the mechanism of multidrug resistance.