Photoredox Catalyzed Cyclization of Enaminones/Ketene N,S‑Acetals with β‑Ketodinitriles to Access Polysubstituted Pyrroles
收藏Figshare2025-09-15 更新2026-04-28 收录
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https://figshare.com/articles/dataset/Photoredox_Catalyzed_Cyclization_of_Enaminones_Ketene_i_N_i_i_S_i_Acetals_with_Ketodinitriles_to_Access_Polysubstituted_Pyrroles/30124592
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A facile synthesis of polyfunctionalized pyrroles has been explored via photoredox cascade cyclization of enaminones/ketene N,S-acetals with β-ketodinitriles using eosin Y, CuI, and Ag2CO3 in acetonitrile under blue LED irradiation at room temperature. The present report offers an efficient and straightforward approach to pyrrole-3-carboxylic acids and pyrrole-3-carboxamides with wide substrate scope and functional group tolerance.
创建时间:
2025-09-15



