Note: CpG sites in bold font were found to be significantly associated with callous-unemotional traits The Factor Loadings of each CpG Site onto the Principal Component of Overall HTR1B Methylation.
5-mC is an epigenetic modification of the DNA base cytosine with roles in gene silencing events, imprinting and X inactivation. Phenobarbital (PB) is a well studied non-genotoxic carcinogen with roles
CpG island recovery assay of HEK293T cells was performed using unmethyl collector kit (Activ motif). The precipitated DNAs using recombinant CXXC domain were analyzed by deep sequencing along with the
Additional file 4. Augmented EPICv2 manifest. A .csv file containing a new version of the manifest with additional information to aid interpretation and analysis of data.
aall forward primers (top) included the following common sequence at the 5′ end: AGGAAGAGAG; all reverse primers (bottom) the sequence CAGTAATACGACTCACTATAGGGAGAAGGCT.
