Electrocardiograph parameters of cd8−/− mice adoptively transferred with CD8+ cell from ifnγ−/−pfn+/+ or ifnγ+/+pfn−/− and infected with the Colombian T. cruzi strain.

1cd8−/− mice were: NI, non-infected; T. cruzi, infected with 100 bt forms of the Colombian T. cruzi strain 15 days after adoptive cell transfer (AdT) of CD8-enriched cells (≥98%), obtained from IFNγ-deficient (ifnγ−/−pfn+/+) or Pfn-deficient (ifnγ+/+pfn−/−) mice.2ECG parameters were evaluated using the following standard criteria: (i) heart rate (monitored by beats per minute (bpm), and (ii) the variation of the P wave and PR, QRS and corrected QT intervals (QTc), all measured in milliseconds (ms). ART, arrhythmia; AVB1, first-degree atrioventricular block; AVB2, second-degree atrioventricular block.3This table represented accumulated data from three independent experiments, with 3 to 5 mice/group in each experiment.4Significant differences:*, pcd8−/− noninfected and T. cruzi-infected mice;#, pcd8−/− non-reconstituted and cd8−/− reconstituted and infected with T. cruzi.